What Is Therapeutic Hypothermia?
Therapeutic hypothermia refers to a form of treatment that is aimed at altering the body temperature in order to modify the pathogenesis of the disease and support the recovery of patients. It is a type of targeted temperature management or TTM that involves strict temperature control, especially in patients with cardiac arrest. There is evidence suggesting that TTM may improve the patient's chances of neurologically intact survival, when administered after cardiac arrest. The protocol of therapeutic hypothermia may vary among different healthcare centers with some targeting T36C while some targeting T33C. The treatment is administered keeping in mind the phases of cerebral blood flow after cardiac arrest as given below: · Phase 1: Multifocal no-reflow · Phase 2: Global hypothermia due to CPR · Phase 3: Delayed hypoperfusion in the initial 24 hours after the ROSC (Return of spontaneous circulation) that may lead to cerebral ischemia due to t